People¶
Agnès Landemard¶
Postdoc @ Cortexlab, UCL, UK
I started using functional ultrasound imaging during my PhD, studying the representation of natural sounds in ferret auditory cortex in ENS, Paris with Yves Boubenec and Shihab Shamma. I’m now a postdoc with Matteo Carandini in UCL, London. I am interested in brainwide dynamics in relation with spontaneous fluctuations in behavioral state and arousal. In all of these projects, I have been working with awake, head-fixed animals implanted with a cranial window. I am interested in the (collaborative?) development of denoising and preprocessing methods, as well as combining fUSi with other methods (optogenetics, electrophysiology, fiber photometry...).
Tags: Mouse, internal states
Links: Website · eLife 2021 · bioRxiv 2025
JC Mariani¶
Postdoc in Alessandro Gozzi’s lab, IIT, Rovereto, Italy
I started doing fUSI during my PhD on pharmaco fUSI (ph-fUSI) with Zsolt Lenkei in 2018. Trained by Jeremy Ferrier on anaesthetised, thinned skull rats, I later moved to awake mice and developed with Andrea Kliewer a end-to-end protocol for standardised ph-fUSI in head fixed, behaving mice in a floating cage. During the second half of my PhD I worked extensively with Samuel Diebolt on denoising for awake transcranial fUSI to do resting state functional connectivity. Together and with Thomas Deffieux we initiated the fUSI-BIDS extension proposal to facilitate curation and exchange of fUSI data. I am now doing a postdoc in Alessandro Gozzi’s lab, where I work on more fundamental questions on the emergence of rs-FC. I am using data coming from both fMRI and fUSI to build models of how brain infraslow dynamics emerge at rest.
Tags: Computationalist, Functional Connectivity, Mouse, analysis
Links: Website
Samuel Le Meur-Diebolt¶
Postdoc @ Cortexlab, UCL, UK
I started working with fUSI when I was invited as an intern by Jean-Charles Mariani and Zsolt Lenkei in the Lenkei team. I then continued as a PhD in collaboration with the Lenkei team, the Physics for Medicine lab, and the Iconeus company, working on improving the usability of fUSI for applications in pharmacological studies of awake mice. We worked extensively on benchmarking denoising strategies for awake fUSI, and applied them to projects studying the effects of opioids, cannabinoids, and psilocybin on the awake mouse brain. I'm now a research fellow at the Cortexlab, working on improving fUSI methods and applying them to studying macroscopic patterns of brain activity organized across brain structures. I am passionate about developing tools and software to improve the usability of fUSI in neuroscience, including ConfUSIus, a Python package for analysis and visualization of fUSI data, and the fUSI-BIDS extension proposal to support fUSI data in the Brain Imaging Data Structure.
Tags: Mouse, functional connectivity, denoising, software